Fotobiomodulação em acidentes ofídicos: análise de marcadores inflamatórios

Abstract

Ophidic accidents represent a significant public health problem in the Amazon region, with emphasis on envenomations caused by snakes of the Bothrops genus, which frequently evolve with a substantial local and systemic inflammatory response. This study aimed to evaluate the effects of low-level laser photobiomodulation on inflammatory markers (CRP, ESR, LDH, AST, and ALT) in patients who were victims of Bothrops snakebites. This is a quantitative, observational, and analytical study conducted with 60 patients hospitalized at the Dr. Heitor Vieira Dourado Tropical Medicine Foundation, 30 of whom were treated with photobiomodulation and 30 assigned to the control group. Clinical and laboratory data were obtained from medical records and analyzed using appropriate statistical tests. The results demonstrated that patients subjected to photobiomodulation showed a significant reduction in CRP, ESR, LDH, and AST levels, with a downward trend also observed for ALT, suggesting modulation of the inflammatory response and a possible tissue-protective effect. It is concluded that low-level laser photobiomodulation represents a promising complementary intervention in the management of Bothrops snakebites, especially in contexts with limited access to specialized treatments, such as in the Amazon region.