Níveis séricos de 25-hidroxivitamina D em idosos com Diabetes mellitus tipo 2 atendidos em um Hospital Universitário de Ribeirão Preto (SP).

Abstract

Study Design: a cross-sectional, descriptive and quantitative study. Objectives: To quantify the serum levels of 25-hydroxyvitamin D 25 (OH) D in elderly patients with diabetes mellitus type 2 (TD2) and the associated epidemiological profile. Methods: dosage of 25(OH)D in patients ≥ 60 years and diagnosis of confirmed T2D. Results: 81 patients were included, 59 women and 29 men aged 69,77 (± 7,30) years. Whites: 64,20%; Browns: 19,75%; Blacks: 9,88%; Yellows: 6,17%. Vitamin D supplementation: 12,34%. Serum level of 25(OH)D: 24,63 (± 7,89) ng/mL - insufficiency; 23,46% sufficient, 28,40% deficient and 48,15% insufficient. Men: 26,57 (± 8,33) ng/mL, Women: 23,42 (± 6,66) ng/ml (t-Test p = 0,0348). For BMI: normal weight 24,33 (± 8,02) ng /mL, overweight: 26,74 (± 6,93) ng /mL, obesity grade I: 20,94 (± 8,32) ng/mL, obesity grades II and III: 18,78 (± 8,75) ng/mL (ANOVA One way p = 0,0189). By glycemic control - HbA1c <7,5%: 27,85 (± 7,70) ng/mL; ≥7,5%: 20,71 (±6,50) ng/mL (t-Test = 0.001). Glucose Fasting <130 mg/dL: 26,87 (± 7,57) ng/mL, >130 mg/dL: 22,04 (± 6,91) ng/mL (t-Test = 0,003). Postprandial glycemia <180 mg/dL: 25,54 (± 7,22) ng/mL, ≥180 mg/dL: 21,24 (±6,49) ng/mL (t-Test p = 0,003). Conclusion: there was a high prevalence of hypovitaminosis D in elderly patients with T2D, higher in women and obese patients in grades II and III. Possible causes: obesity, metabolic syndrome, menopause and low sun exposure. We identified an inverse relationship between serum 25 (OH) D levels and glycemic control variables (HbA1c, GJ and GPP).