Navegando por Autor "Coletta, Marcus Vinicius Della"
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Item Neurocriptococose cursando com síndromes parkinsoniana e demencial de lenta progressão(Universidade do Estado do Amazonas, 2019-01-21) Rabelo, Ronaldo Marques Pontes; Birman, Denis; Vieira, Karoliny da Silva; Rodrigues, Marcus Vinicius Gomes; Oliveira, Mariza Marques de; Coletta, Marcus Vinicius DellaCentral nervous system's infection by Cryptococcus neoformans occurs in both immunocompetent and in immunosuppressed patients; common symptoms include headache, photophobia, nausea and decreased level of consciousness. This clinical picture is nonspecific and contributes to the delay in diagnosis, which increases the risk of permanent sequelae. However, some patients have atypical symptoms that do not direct the clinical rationale for this agent. Treatment is based on antifungal therapy including amphotericin B and/or imidazole derivatives and repeated lumbar punctures, to reduce intracranial pressure, which is also directly related to the outcome. We report the case of a middle-aged man, with atypical clinical picture, including slowly, progressive parkinsonian and psychiatric symptoms. Lumbar puncture revealed the presence of that fungus in cerebrospinal fluid. Proper treatment allowed general symptomatic and important clinical improvement. Key words: Secondary Parkinson disease – Cryptococcus – EncephalitisItem Prevalência da síndrome das pernas inquietas em população de idosos universitários da cidade de Manaus (UEA-UNATI)(Universidade do Estado do Amazonas, 2019-01-18) Almeida, Carlos Maurício Oliveira de; Oliveira, Fernanda Paz de; Farias, Stephanie Ramos de; Fernandes, Eduardo; Ribeiro, Euler Esteves; Coletta, Marcus Vinicius DellaRestless legs syndrome (RLS) is a disorder of sensor motor integration, which affects approximately 5 to 10% of the population. Studies in certain population groups, especially in healthy elderly in the north of the country, are still scarce. To determine the prevalence of RLS; to assess the severity of symptoms through the RLSRS; to check for the presence of sleepiness and sleep complaints. This was an observational, cross-sectional study. Participants were interviewed with a questionnaire created on basis of the RLSRS criteria. Analyses were performed using MINITAB version 14.1. 82 elderly people were interviewed. The mean age was 69 years (± 4.18 years), with 81.8% female and 18.2% male, with a female to male ratio of 4.5:1. The prevalence of RLS in this population was 13.4% (N=11). Among the affected, 62.3% had moderate RLS symptoms and 37.5% had mild degree. The average RLSRS score was 11.5 points (± 6.62) and none showed scores above 20 (severe/very severe). Sleep disorders (SD) were present in 50% of the participants, which were graded as Light (25%), Moderate (12.5%) and Intense (12.5%). There was no evidence of association between age and the degree of RLS (p = 0.71), nor between gender and the severity of symptoms (p = 0.37). RLS is a highly prevalent condition and still under-diagnosed and treated in the elderly population of the Amazon region. Keywords: Restless legs; elderly; Amazon; University.Item Síndrome das pernas inquietas em unidades de hemodiálise em Manaus(Universidade do Estado do Amazonas, 2019-01-18) Coletta, Marcus Vinicius Della; Bezerra, Torben Cavalcante; Gonçalves, Júlia Jaqueline MendonçaRestless legs syndrome (RLS) is a sensorimotor disorder characterized by an urge or need to move the limbs and variable discomfort. Chronic renal failure (CRF) is an important cause of secondary RLS. The aim of this study was to assess the frequency of RLS in CRF patients in a hemodialysis unit in Manaus. 57 patients with CRF were assessed. A clinical protocol was used for personal dates, medical dates, and criteria provided by International Restless Legs Syndrome Study Group. Biochemical and hematological values were obtained. The frequency of RLS was 14% (08 patients). There was not difference in hematologic and biochemical tests. The frequency is considerable and suggests an important presence of the Restless Legs Syndrome in the population of patients in hemodialysis. Further biochemical studies are necessary to elucidate the pathophysiology of RLS in patients with renal failure. Keywords: Restless Legs Syndrome, chronic renal failure.